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Int J Clin Exp Pathol 2011;4(2):210-214
Case Report
Angiolipomatous mesenchymal hamartoma (angiolipomatosis) of the sigmoid mesocolon
Resit Demir, Axel Schmid, Werner Hohenberger, Abbas Agaimy
Department of general and visceral surgery, Department of Radiology and Institute of Pathology, Erlangen University Hospital, 91054 Erlangen,
Germany.
Received January 20, 2011; accepted January 25, 2010; Epub January 26, 2011; published February 15, 2011
Abstract: Background: Primary mesenteric tumors are exceedingly rare and may thus pose a diagnostic challenge. They encompass both
benign and malignant neoplasms as well as reactive and idiopathic tumefactive fibroinflammatory lesions. Method and results: A 70-year-old
man who was diagnosed with sigmoid colon cancer was found to have a large non-homogeneous predominantly fatty retroperitoneal soft
tissue mass on computerized tomography (CT) scan. The mass was attached to the aorta and have encased the inferior mesenteric artery and
extended into the sigmoid mesocolon. Histological examination of the mass showed ill-defined lipoma-like mature fatty tissue traversed by
paucicellular fibrous septa entrapping small nerves and containing remarkably increased venous blood vessels reminiscent of soft tissue
angiomatosis without evidence of malignancy. The histological features were consistent with an angiolipomatous hamartomatous
mesenchymal proliferation. Conclusions: Angiolipomatous hamartoma might be histogenetically related to soft tissue angiomatosis. To our
knowledge, this case represents the first well documented lesion of this type at this location and must be distinguished from other
fat-containing masses, particularly angiomyolipoma, sclerosing mesenteritis and mesenteric liposarcoma. (IJCEP1101005).
Keywords: Angiolipomatous hamartoma, mesocolon, angiomatosis, tumor-like lesion
Full text PDF
Address all correspondence to:
Dr. Abbas Agaimy
Pathologisches Institut, Universitätsklinikum Erlangen
Krankenhausstrasse 12, 91054, Erlangen,
Germany.
Tel: +49-9131-85-22288, Fax: +49-9131-85-24745
E-mail: abbas.agaimy@uk-erlangen.de
Case Report
Angiolipomatous mesenchymal hamartoma (angiolipomatosis) of the sigmoid mesocolon
Resit Demir, Axel Schmid, Werner Hohenberger, Abbas Agaimy
Department of general and visceral surgery, Department of Radiology and Institute of Pathology, Erlangen University Hospital, 91054 Erlangen,
Germany.
Received January 20, 2011; accepted January 25, 2010; Epub January 26, 2011; published February 15, 2011
Abstract: Background: Primary mesenteric tumors are exceedingly rare and may thus pose a diagnostic challenge. They encompass both
benign and malignant neoplasms as well as reactive and idiopathic tumefactive fibroinflammatory lesions. Method and results: A 70-year-old
man who was diagnosed with sigmoid colon cancer was found to have a large non-homogeneous predominantly fatty retroperitoneal soft
tissue mass on computerized tomography (CT) scan. The mass was attached to the aorta and have encased the inferior mesenteric artery and
extended into the sigmoid mesocolon. Histological examination of the mass showed ill-defined lipoma-like mature fatty tissue traversed by
paucicellular fibrous septa entrapping small nerves and containing remarkably increased venous blood vessels reminiscent of soft tissue
angiomatosis without evidence of malignancy. The histological features were consistent with an angiolipomatous hamartomatous
mesenchymal proliferation. Conclusions: Angiolipomatous hamartoma might be histogenetically related to soft tissue angiomatosis. To our
knowledge, this case represents the first well documented lesion of this type at this location and must be distinguished from other
fat-containing masses, particularly angiomyolipoma, sclerosing mesenteritis and mesenteric liposarcoma. (IJCEP1101005).
Keywords: Angiolipomatous hamartoma, mesocolon, angiomatosis, tumor-like lesion
Full text PDF
Address all correspondence to:
Dr. Abbas Agaimy
Pathologisches Institut, Universitätsklinikum Erlangen
Krankenhausstrasse 12, 91054, Erlangen,
Germany.
Tel: +49-9131-85-22288, Fax: +49-9131-85-24745
E-mail: abbas.agaimy@uk-erlangen.de
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