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Int J Clin Exp Pathol 2(1),99-103;2009
Case Report
Multicentric Infarcted Leiomyoadenomatoid Tumor: A Case Report
Ran Hong, Dong-Youl Choi, Sang Joon Choi and Sung-Chul Lim
Departments of 1Pathology and Obstetrics and Gynecology, College of Medicine, Chosun University, Gwangju, Korea
Received January 31, 2008; accepted and available online February 11, 2008
Abstract:Adenomatoid tumor is a benign, usually small lesion that may be found within the wall of fallopian tubes or beneath the uterine
serosa near the uterine cornu. It is often accompanied by smooth muscle hypertrophy that may obscure the adenomatoid tumor. We herein
report a very unusual case of infarcted leiomyoadenomatoid tumor of the uterus and ovary in a 24-year-old woman who presented with severe
lower abdominal pain and masses in the uterus and right ovary. Pelvic ultrasonography and computed tomography revealed a 5 cm mass in
the myometrium and a 4 cm mass in the right ovary. Laparoscopy-assisted transvaginal mass removal was performed under the clinical
impression of a uterine leiomyoma and benign ovarian teratoma. On a microscopic examination, prominent fascicles of smooth muscle
separated or infiltrated by cuboidal or signet ring-like vacuolated cells, as well as tubular formations lined by flattened mesothelial cells and
extensive necrosis were observed in both masses. The microscopic appearance often suggested the possibility of a malignant neoplasm due
to irregular pseudoinfiltration with atypical cuboidal cells and the paucity of a typical adenomatoid tumor due to infarction, and the presence of
epithelial-appearing cells in the hypertrophic smooth muscle bundles that mimicked an infiltrating carcinoma for a leiomyoma or myometrium.
These unemphasized features of leiomyoadenomatoid tumors may potentially lead to more aggressive therapy than warranted if not correctly
interpreted, especially for infarcted cases. (IJCEP801004).
Key Words: Leiomyoadenomatoid tumor, uterus, ovary, infarction
Full text: PDF
Address all correspondence to: Sung-Chul Lim, M.D., Ph.D., Department of Pathology, Chosun University Hospital, 588, Seosuk-dong,
Dong-gu, Gwangju, Korea. Tel: 82-62-230-6343; Fax: 82-62-226-5860; Email: sclim@chosun.ac.kr
Case Report
Multicentric Infarcted Leiomyoadenomatoid Tumor: A Case Report
Ran Hong, Dong-Youl Choi, Sang Joon Choi and Sung-Chul Lim
Departments of 1Pathology and Obstetrics and Gynecology, College of Medicine, Chosun University, Gwangju, Korea
Received January 31, 2008; accepted and available online February 11, 2008
Abstract:Adenomatoid tumor is a benign, usually small lesion that may be found within the wall of fallopian tubes or beneath the uterine
serosa near the uterine cornu. It is often accompanied by smooth muscle hypertrophy that may obscure the adenomatoid tumor. We herein
report a very unusual case of infarcted leiomyoadenomatoid tumor of the uterus and ovary in a 24-year-old woman who presented with severe
lower abdominal pain and masses in the uterus and right ovary. Pelvic ultrasonography and computed tomography revealed a 5 cm mass in
the myometrium and a 4 cm mass in the right ovary. Laparoscopy-assisted transvaginal mass removal was performed under the clinical
impression of a uterine leiomyoma and benign ovarian teratoma. On a microscopic examination, prominent fascicles of smooth muscle
separated or infiltrated by cuboidal or signet ring-like vacuolated cells, as well as tubular formations lined by flattened mesothelial cells and
extensive necrosis were observed in both masses. The microscopic appearance often suggested the possibility of a malignant neoplasm due
to irregular pseudoinfiltration with atypical cuboidal cells and the paucity of a typical adenomatoid tumor due to infarction, and the presence of
epithelial-appearing cells in the hypertrophic smooth muscle bundles that mimicked an infiltrating carcinoma for a leiomyoma or myometrium.
These unemphasized features of leiomyoadenomatoid tumors may potentially lead to more aggressive therapy than warranted if not correctly
interpreted, especially for infarcted cases. (IJCEP801004).
Key Words: Leiomyoadenomatoid tumor, uterus, ovary, infarction
Full text: PDF
Address all correspondence to: Sung-Chul Lim, M.D., Ph.D., Department of Pathology, Chosun University Hospital, 588, Seosuk-dong,
Dong-gu, Gwangju, Korea. Tel: 82-62-230-6343; Fax: 82-62-226-5860; Email: sclim@chosun.ac.kr
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