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Int J Clin Exp Pathol 2(1), 11-20; 2009
Original Article
Pitfalls in Diagnostic Hematopathology: Part I
Xianfeng F. Zhao
Department of Pathology, University of Maryland School of Medicine, Baltimore, MD
Received 4 April 2008; Accepted and available online 21 April 2008
Abstract: Pitfalls in diagnostic hematopathology are underestimated and underreported. Major causes of diagnostic error in hematopathology
include: 1) inadequate material; 2) inadequate workup; 3) inadequate clinical correlation; 4) over or under interpretation; 5) challenges in
hematopathology. In the first part of this review series, I will focus on the pitfalls in diagnosing and differentiating chronic lymphocytic
leukemia/small lymphocytic lymphoma (CLL/SLL) and mantle cell lymphoma, and discuss the strategies to avoid potential diagnostic errors
based on my personal experience. (IJCEP804001).
Key Words: Hematopathology, pitfall, mantle cell lymphoma, chronic lymphocytic leukemia/small lymphocytic
lymphoma
Full text PDF
Address all correspondence to: X. Frank Zhao, M.D., Ph.D., Department of Pathology, University of Maryland School of Medicine, 10 S. Pine
Street, MSTF 611B, Baltimore, MD 21201, Tel: 410-328-2146, Fax: 410-328-5508, E-mail: xzhao@umm.edu
Original Article
Pitfalls in Diagnostic Hematopathology: Part I
Xianfeng F. Zhao
Department of Pathology, University of Maryland School of Medicine, Baltimore, MD
Received 4 April 2008; Accepted and available online 21 April 2008
Abstract: Pitfalls in diagnostic hematopathology are underestimated and underreported. Major causes of diagnostic error in hematopathology
include: 1) inadequate material; 2) inadequate workup; 3) inadequate clinical correlation; 4) over or under interpretation; 5) challenges in
hematopathology. In the first part of this review series, I will focus on the pitfalls in diagnosing and differentiating chronic lymphocytic
leukemia/small lymphocytic lymphoma (CLL/SLL) and mantle cell lymphoma, and discuss the strategies to avoid potential diagnostic errors
based on my personal experience. (IJCEP804001).
Key Words: Hematopathology, pitfall, mantle cell lymphoma, chronic lymphocytic leukemia/small lymphocytic
lymphoma
Full text PDF
Address all correspondence to: X. Frank Zhao, M.D., Ph.D., Department of Pathology, University of Maryland School of Medicine, 10 S. Pine
Street, MSTF 611B, Baltimore, MD 21201, Tel: 410-328-2146, Fax: 410-328-5508, E-mail: xzhao@umm.edu
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